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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN1
All Species:
10.3
Human Site:
S562
Identified Species:
17.44
UniProt:
O75460
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75460
NP_001424.3
977
109735
S562
D
D
G
D
E
E
T
S
V
V
I
V
G
K
I
Chimpanzee
Pan troglodytes
XP_511585
968
108684
P551
L
R
E
S
D
E
H
P
N
V
I
R
Y
F
C
Rhesus Macaque
Macaca mulatta
XP_001109583
1070
119711
S655
D
D
G
D
E
E
T
S
M
V
I
V
G
K
I
Dog
Lupus familis
XP_853409
975
109686
S560
D
D
E
D
E
E
T
S
M
V
I
V
G
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQY0
977
110166
R562
D
D
E
D
E
E
T
R
M
V
I
V
G
K
I
Rat
Rattus norvegicus
XP_573211
965
109012
R550
D
D
E
D
E
E
T
R
M
V
I
V
G
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510886
942
106736
N523
E
E
A
D
D
E
T
N
V
V
V
V
G
K
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085649
958
108223
D553
E
S
E
A
S
D
A
D
E
I
R
V
G
K
I
Zebra Danio
Brachydanio rerio
XP_001919350
921
102695
E523
N
E
Q
A
D
V
V
E
V
G
K
I
S
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097839
1074
120152
G539
D
L
V
D
L
G
N
G
Q
V
R
V
G
K
I
Honey Bee
Apis mellifera
XP_392044
968
110555
T527
L
G
K
G
C
E
G
T
F
V
Y
R
G
N
F
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
T537
G
T
V
V
Y
R
G
T
F
D
G
R
E
V
A
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
G504
G
D
D
Y
V
P
E
G
F
V
K
V
G
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
N665
S
R
I
A
N
I
P
N
F
E
Q
S
L
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.7
90.3
95.5
N.A.
93.1
92.1
N.A.
83
N.A.
56
57
N.A.
37.7
43
41.3
41.4
Protein Similarity:
100
84.8
91
97.3
N.A.
96.3
94.8
N.A.
89.3
N.A.
71.4
69.8
N.A.
52.9
58.6
59.3
54.4
P-Site Identity:
100
20
93.3
86.6
N.A.
80
80
N.A.
60
N.A.
26.6
6.6
N.A.
46.6
20
0
40
P-Site Similarity:
100
26.6
100
93.3
N.A.
86.6
86.6
N.A.
93.3
N.A.
46.6
33.3
N.A.
46.6
26.6
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
22
0
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
43
43
8
50
22
8
0
8
0
8
0
0
0
0
0
% D
% Glu:
15
15
36
0
36
58
8
8
8
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
29
0
0
0
0
15
8
% F
% Gly:
15
8
15
8
0
8
15
15
0
8
8
0
72
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
0
8
43
8
0
0
65
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
15
0
0
72
0
% K
% Leu:
15
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
8
15
8
0
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
15
0
0
0
8
0
15
0
0
15
22
0
0
0
% R
% Ser:
8
8
0
8
8
0
0
22
0
0
0
8
8
0
8
% S
% Thr:
0
8
0
0
0
0
43
15
0
0
0
0
0
0
0
% T
% Val:
0
0
15
8
8
8
8
0
22
72
8
65
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _